München 2004 – wissenschaftliches Programm

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MS: Massenspektrometrie

MS 7: Poster

MS 7.10: Poster

Donnerstag, 25. März 2004, 14:00–16:00, Schellingstr. 3

Dynamical Concept to Resolve Single-Single Chemical Transformation — •Victor Wei-Keh Wu — Department of Electronic Engineering, Lan-Yang Institute of Technology, 261-02 Tou-Cheng, I-Lan, Taiwan, ROC., Fax:+886-(0)3-977-4483, Tel:-977-1997-ext-231(O), +886-0919-300-525(direct), Email:victorbres3tw@yahoo.com.tw

Investigation of dynamic behavior(s) is the only way to know the transformation as well as conformational mechanism of a chemical reaction, and then to manipulate its route(s) and mechanism(s). The new challenging trend to investigate biomolecular reaction dynamics comparing with the traditional simple atomic and molecular reaction dynamics (3 4 atomic system) is much more complicated and difficult as thought. The recently developed experimental method of FRET (Fluorescence Resonance Energy Transfer) or spFRET - NSOM (Near-field Scanning Optical Microscopy, because of the difficult pronunciation it is often called as SNOM), eventual combined with Optical Tweezer, combining with MALDI (Matrix Assisted Laser Desorption Ionization - Time of Flight Mass spectroscopy) is quite full of promises. All of these investigations must be limited within a small intra- or intermolecular interacting region, as well as for a system of limited number of atoms of both interacting functional groups or sites, whatever the results of simulation can be also satisfied. Ref. V. W.-K. Wu, Verh. Dtsch. Phys. Ges., 62(2), 161, MS3.7 (1998). The author is at the same time in charge of Victor Basic Research Laboratory e. V., Bielefeld, Germany (Email: 1. victorbres@yahoo.de, 2. victorbres3tw@yahoo.com.tw, http://www.uni-bielefeld.de/ fkure, Telefax:+49-(0)521-5213339)