Regensburg 2004 – wissenschaftliches Programm

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AKB: Biologische Physik

AKB 23: Membranes

AKB 23.1: Hauptvortrag

Dienstag, 9. März 2004, 16:30–17:00, H40

Microscopy and Spectroscopy on Single Membrane Proteins — •Jörg Wrachtrup, Carsten Tietz, Margarita Khazarchyan, and Thews Elmar — Universität Stuttgart, 3. Physikalisches Institut

The membrane environment is of vital importance for the function of most cellular receptors. Either stability requires the lipid bilayer or receptor function is related to oligomerisation in the membrane. The contribution will describe single-molecule studies of photoreceptors in membranes under ambient conditions as well as low temperature. Life cell studies with fluorescence correlation sprectroscopy and burst width analysis reveals clustering of TNF receptors as well as details of the diffusion behaviour of second messengers in the apoptotic signalling pathway.