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Regensburg 2004 – wissenschaftliches Programm

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AKB: Biologische Physik

AKB 50: Poster Session "Biological Physics"

AKB 50.130: Poster

Freitag, 12. März 2004, 10:30–13:00, B

Dissipative Micro-Domain Formation in Transferred Lipid / Lipopolymer Monolayers — •Oliver Purrucker1, Anton Förtig2, Rainer Jordan2, and Motomu Tanaka11Technische Universität München, Lehrstuhl für Biophysik E22, James-Franck-Str., D-85748 Garching — 2Technische Universität München, Lehrstuhl für Makromolekulare Stoffe, Lichtenbergstr. 4, D-85748 Garching

Ultra-thin (d < 10 nm) liquid films that No-dqwetNo-dq solid surfaces can be stabilized by surfactant films covering the air/liquid interface. E.g., single chain surfactants can increase the thickness of a glucose solution by two orders of magnitude1. Langmuir monolayers of lipid/lipopolymer mixtures can be treated as models of cell surfaces, where hydrated polymer films create high osmotic pressures to stabilize membrane structures2.

Here, we observed that Langmuir-Blodgett lipid/lipopolymer monolayers form stripe-like microscopic domains that align parallel to the transfer direction. Systematic characterization before and after transfer demonstrated that formation of such micro-domains is not caused by thermodynamic phase separation. Width and spacing of stripes are clearly dependent on transfer velocity, suggesting a formation due to hydrodynamic forces operating within ultra-thin liquid films between lipids and substrates.

(1) G. Elender, E. Sackmann, J. Phys. II France 4 (1994) 455

(2) E. Sackmann, M. Tanaka, Trends Biotechnol. 18 (2000) 58

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