Berlin 2005 – scientific programme

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AKB: Biologische Physik

AKB 100: Poster Session I

AKB 100.16: Poster

Saturday, March 5, 2005, 16:45–18:45, Poster TU D

Measurement of viscoelastic properties of lipid membranes on a chip — •Daniel Steppich, Achim Wixforth und Matthias F. Schneider — Lehrstuhl für Experimentalphysik I, Biophysik, Universität Augsburg, Universitätsstr. 1, 86135 Augsburg

Lipid membranes can strongly affect the properties of the biological cells by an enormous change of their physical behaviour induced by small changes in specific external conditions. A premise for the understanding of many biological processes is therefore the knowledge of the viscoelastic properties, e.g. the compressibility and the elasticity. The viscoelastic properties of lipid bilayers are investigated with surface acoustic waves (SAW) using a novel designed biochip. Since SAWs have a higher accuracy in determine the mass loading or the absorption on surfaces, because of the operating frequencies over 100 MHz. We can also adjust our chips to specific questions, such as mass loading, viscosity or fluidics by the chip design, which results in different types of SAWs. In addition we study the effects of different parameters, e.g. changing in temperature or pH, and the elastic properties of soft films in an aqueous environment.