Berlin 2005 – scientific programme

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AKB: Biologische Physik

AKB 100: Poster Session I

AKB 100.20: Poster

Saturday, March 5, 2005, 16:45–18:45, Poster TU D

Nanoquakes meet Soft Materials — •Matthias F. Schneider and Achim Wixforth — a

Surface acoustic waves (SAW) are applied to mimic protein tissue and cell-tissue interactions. In contrast to flow chamber experiments the experiments are done on an open, plane surface allowing to manipulate and optically monitor the experiment simultaneously. For the first time the unfolding of proteins under shear flow conditions could be shown, underlining the potential of this technique for mimicking blood flow scenarios. Furthermore shear waves are used as biosensors in the sense of viscoelasticity experiments under dynamic conditions. Here we study the kinetics of adsorption/adhesion of membranes and cells on functionalized surfaces and follow the time course of protein membrane interactions.