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AKB: Biologische Physik
AKB 100: Poster Session I
AKB 100.40: Poster
Samstag, 5. März 2005, 16:45–18:45, Poster TU D
Dynamics of DNA Condensation Investigated by Small Angle X-Ray Microdiffraction — •Rolf Dootz1, Alexander Otten2, Bernd Struth3, and Thomas Pfohl1,2 — 1Max-Planck-Institut für Strömungsforschung, Bunsenstrasse 10, D-37073 Göttingen — 2Angewandte Physik, Universität Ulm, Albert-Einstien-Allee 10, D-89069 Ulm — 3European Synchrotron Radiation Facility, 6 rue Horovitz, B.P. 220, F-38043 Grenoble Cedex
The combination of x-ray microdiffraction and microfluidics is used to investigate the dynamic behavior of soft materials. A microfocused x-ray beam enables the observation of the association of biomaterials inside microfluidic channels. Using a hydrodynamic focussing device, the evolution of the DNA condensation induced by polyimine dendrimers as well as by histone proteins can be studied. Due to an extensional flow at the center of this device alignment of the material is induced which allows for an improved structural characterization. Furthermore, the influence of strain applied to these materials can be tested.