Berlin 2005 – scientific programme

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CPP: Chemische Physik und Polymerphysik

CPP 29: POSTER: Polymer physics

CPP 29.31: Poster

Tuesday, March 8, 2005, 16:30–18:30, Poster TU D

The interaction between single colloids with and without grafted DNA as measured by optical tweezers — •Kati Kegler, Christof Gutsche, Mathias Salomo, and Friedrich Kremer — Institute for Experimental Physics I, University of Leipzig, Linnestr. 5, 04103, Leipzig, Germany

Optical Tweezers (OT) are extraordinary microscopic tools with nanometer resolution in 3-D space and sub pico newton - resolution in force. They are used to measure the interaction potential between single pairs of colloids grafted with (genetically engineered) DNA of varying length (base pairs (bp), 1000 bp, 2000 bp and 4000 bp). The interaction forces are measured in two dimensions - parallel and perpendicular to the axis between the two colloids. This enables one to measure the effective thickness of the DNA layer and its elastic properties.