Berlin 2005 – wissenschaftliches Programm
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M: Metallphysik
M 2: Flüssige und amorphe Metalle I
M 2.1: Vortrag
Freitag, 4. März 2005, 10:30–10:45, TU H111
Electrochemistry and biocompatibility of Zr-based Bulk Metallic Glasses — •Stefano Buzzi1, Kaifeng Jin1, Samuele Tosatti2, Isabel Gerber3, Peter J. Uggowitzer1, and Jörg F. Löffler1 — 1Laboratory of Metal Physics and Technology, ETH Zürich, 8093 Zürich, Switzerland — 2Biomedical Interfaces Team, Laboratory for Surface Science and Technology, ETH Zürich, Switzerland — 3Institute of Cell Biology, ETH Zürich, Switzerland
Bulk metallic glasses are promising materials for medical applications because of their high strength and elasticity. In order to determine their biocompatibility as a function of sample preparation, a selected group of these materials was characterized by XPS and electrochemical methods (potentiodynamic measurements and solution analysis). Their cytotoxicity was also analyzed by measuring the viability and metabolic activity of a mouse fibroblast cell line. The results indicate that pitting corrosion takes place in the presence of chloride-ion concentrations comparable to body conditions. Furthermore, it was shown that plasma treatment stabilizes the natural ZrO2 adlayer, and that the cells are able to grow on the Zr-based glasses with good viability and metabolic activity. Among the Zr-based alloys, the most metabolic activity was observed in a Ni-free alloy developed by our group. In contrast, the cells cultured on the Cu-Ti-based metallic glasses hardly grew at all.