Berlin 2005 – scientific programme
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SYBN: Biological and Social Networks
SYBN 3: Biologische und Soziale Netzwerke, Postersitzung
SYBN 3.20: Poster
Monday, March 7, 2005, 14:00–15:30, Poster TU E
Primary Linguistic Units in Genomes — •Stephan Heymann1, Peter Rieger1, and Andreas Schaale2 — 1Humboldt-Universität zu Berlin; Institut für Informatik; Lehrstuhl für Datenbanken und Informationssysteme; Unter den Linden 6; 10099 Berlin — 2contraco Consulting and Software Ltd.; Diepenseestrasse 10; 15732 Waltersdorf
We will present a new method for decomposition of genetic information. This method give rise to primary linguistic units (PLU) along a chromosome (to not use words like ’syllables’ or ’words’), which are derived without any extrinsic assumptions or artificial parameters. We will demonstrate that the proposed decomposition displays linguistic features. We find new information structures irrespective of the molecular service they convey. It turned out that PLU scissoring allows to clearly separate between static noise and information along the chromosomal base sequence. Moreover, we overcome the major dogmatic obstacle of current bioinformatics. This consists in the premature effort to capture semantic and topological organisation of genomes by application of non-metric measures of similarity and distance. In the talk we will demonstrate the force of expression by various life science applications.