Dresden 2006 – wissenschaftliches Programm
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AKB: Biologische Physik
AKB 10: Neuroscience
AKB 10.1: Hauptvortrag
Dienstag, 28. März 2006, 11:30–12:00, ZEU 255
Synaptic Plasticity and Memory from an Optimality Viewpoint — •Wulfram Gerstner1, Taro Toyoizumi1,2, Jean-Pascal Pfister1, and Kazuyuki Aihara2 — 1Ecole Polytechnique Federale de Lausanne, EPFL — 2University of Tokyo
Connections between neurons change and these changes (potentiation and depression of synapses) are thought to be the basis of learning and memory. Despite a diversity of experimental facts, we believe that the rule controlling changes of synapses should be simple. More precisely, we studied the hypothesis that synaptic dynamics is controlled by three basic principles:
(A) Synapses adapt their efficacies so that neurons can effectively transmit information;
(B) homeostatic processes stabilize the mean firing rate of the postsynaptic neuron; and
(C) weak synapses adapt more slowly than strong ones while maintenance of strong synapses is costly.
Our results show that a synaptic update rule derived from these principles depends on spike timing, is sensitive to correlations in the input, and is useful for synaptic memory.