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AKB: Biologische Physik

AKB 20: Nano-Biomaterials and Devices

AKB 20.7: Vortrag

Donnerstag, 30. März 2006, 11:45–12:00, ZEU 255

Rapid Chiral Synthesis of Rigid DNA Building Blocks for Molecular Nanofabrication — •Catherine F. Tardin¹, Russell P. Goodman², Iwan A.T. Schaap¹, C. M. Erben², Richard M. Berry², Andrew J. Turberfield², and Christoph F. Schmidt¹ — ¹Dept. Physics, Vrije Universiteit, Amsterdam, NL — ²Clarendon Laboratory, Department of Physics, University of Oxford, Parks Road, Oxford OX1 3PU, UK

The programmability of base-pairing interactions makes DNA an ideal molecule for construction by self-assembly. Practical components for 3D molecular nanofabrication must be simple to produce, stereopure, rigid and adaptable. We report a family of DNA tetrahedra, less than 10nm in size, that can be made in seconds with near-quantitative yield. Their triangulated architecture allows them to support a compressive load: by compressing a DNA tetrahedron by little more than 1 nm with an AFM we have measured the axial compressibility of DNA and have observed the buckling of the double helix under high loads.