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AKB: Biologische Physik
AKB 21: Intracellular Transport
AKB 21.5: Vortrag
Donnerstag, 30. März 2006, 11:45–12:00, ZEU 260
Driven diffusive gas of dimers: a model for molecular motors collective properties. — •Paolo Pierobon1,2, Thomas Franosch1,2, Mauro Mobilia1, and Erwin Frey1 — 1Arnold Sommerfeld Center, Theresienstr.37, D-80333 Muenchen — 2Hahn Meitner Institut, Glienicker str.100, D-14109 Berlin
One dimensional driven lattice gases have been extensively used to model traffic of molecular motors on microtubules. The standard model is the Totally Asymmetric Simple Exclusion Process (TASEP): a lattice gas model where particles move unidirectionally with a fixed rate and the flux depends on the entrance and exit rate. Inspired by recent models in intracellular transport, we discuss the properties of a TASEP of dimers (representing kinesins or dyneins) without particle conservation in the bulk (on/off kinetics). We investigate the phase diagram and the stationary average density profile by means of Monte Carlo simulations and rationalize the results through a refined mean field theory. We concentrate on experimentally measurable quantities and we investigate the effects of one defect in the lattice.