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CPP: Chemische Physik und Polymerphysik

CPP 24: POSTER Microfluidics

CPP 24.14: Poster

Donnerstag, 30. März 2006, 17:00–19:00, P2

An experimental setup to handle liquids in a nanofluidic device — •Evelyn Meyer and Hans-Georg Braun — Leibniz Institute of Polymer Research, Max-Bergmann Center of Biomaterials, D-01069 Dresden, Hohe Strasse 6

The manipulation of fluids of femto- to picoliter volume in micro or nanosized channels is realized by a piezodriven manipulation unit adapted to an inverse fluorescence microscope. A truncated PDMS pyramid with a basal plane of 20 to 400 micrometer is mounted to a piezomotor system and can be controlled in x,y,z direction and enables filling and sealing of an underlying micro-and nanochannel structure .This assembly allows the encapsulation of DNA molecules for dynamic studies in confined geometries. The success of the filling process depends on the wettability of the microstructured surface according to the Wenzel regime for wetting of rough surfaces. Using an adjustable slit geometry between pyramid and substrate fluids entrapped in the slit can be transported along a substrate with controllable velocity to study the behaviour of propagating fluids on chemical and topographical heterogenous surfaces.