Dresden 2006 – wissenschaftliches Programm

Bereiche | Tage | Auswahl | Suche | Downloads | Hilfe

O: Oberflächenphysik

O 14: Poster session I (Adsorption, Epitaxy and growth, Phase transitions, Surface reactions, Organic films, Electronic structure, Methods) (sponsored by Omicron Nanotechnology GmbH)

O 14.52: Poster

Montag, 27. März 2006, 18:00–21:00, P2

Electrochemical and Thermal Stability of Self-Assembled Mercaptohexanol Monolayers on Gold Surfaces — •Christine Hautmann¹, Kenji Arinaga^1,2, Erika Pringsheim¹, Marc Tornow¹, Shozo Fujita², Naoki Yokoyama², Ulrich Rant¹, and Gerhard Abstreiter¹ — ¹Walter Schottky Institut, Technische Universität München, Garching, Germany — ²Fujitsu Laboratories, Atsugi, Japan

Self assembled monolayers of mercaptoalkanols are widely used to functionalize solid substrates in aqueous environments. Recently, they have gained great importance as an essential element in advanced DNA layer architectures on gold surfaces. In a two-step adsorption process, mercaptohexanol (MCH) is used to backfill exposed surface areas after oligonucleotide assembly. By forming a dense sub-layer MCH prevents non-specific DNA-Au interactions, thus improving the functionality of DNA molecules on the surface. Although this procedure has been adopted by numerous groups, little is known about the durability of mercaptohexanol SAM when exposed to various environmental conditions.

In this contribution, we elucidate the electrochemical as well as thermal stability of MCH-layers in aqueous solutions. Using electrochemical blocking experiments and impedance spectroscopy, we probe the stability of the layers for varying electrochemical substrate potentials. In addition, we study the durability of the layers when repeatedly performing temperature cycles up to 85^∘C. Understanding the behavior of MCH-SAMs under these conditions is essential with respect to the electrical manipulation of DNA on Au surfaces and DNA-sensing in particular.