Regensburg 2007 – wissenschaftliches Programm

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BP: Fachverband Biologische Physik

BP 26: Poster Session II

BP 26.27: Poster

Donnerstag, 29. März 2007, 17:00–19:30, Poster B

Dynamic Force Spectroscopy Experiments: Bayes and Maximum-Likelihood Approach — •Sebastian Getfert and Peter Reimann — Condensed Matter Theory, Universität Bielefeld, Universitätsstraße 25, 33615 Bielefeld

In dynamic force spectroscopy experiments the distribution of rupture forces is measured at different pulling velocities. An analysis of these distributions allows to draw conclusions about the underlying energy landscape.

In the past years a great amount of work has been spent to improve experiment and theory whereas the methods used to connect theory and experiment are still rather basic. Here we discuss, how the information obtained by dynamic force spectroscopy experiments can be used most efficiently to extract the parameters of interest. A detailed statistical analysis also shows which statements concerning the energy landscape are possible and for which pulling velocities measurements should be performed in order to minimize the statistical uncertainties.