Regensburg 2007 – wissenschaftliches Programm

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BP: Fachverband Biologische Physik

BP 26: Poster Session II

BP 26.47: Poster

Donnerstag, 29. März 2007, 17:00–19:30, Poster B

Growth pattern of single fission yeast cells: linear, bilinear, or exponential? — •Stephan Baumgärtner and Iva Tolic-Nørrelykke — Max Planck Institute of Molecular Cell Biology and Genetics, Dresden

The exact growth profile of size parameters during the cell cycle is controversial. Linear, exponential and bilinear models are typically considered. Exponential models assume that the rate of growth is proportional to the existing size. However, growth can be linear, or multi-linear, corresponding to different constant rates separated by rate-change points.

The cylindrically shaped fission yeast cells grow in length by extension at the cell ends. The growth pattern of fission yeast cells is currently unclear: a number of models can be well-fitted to the data, due to the relatively low spatial and temporal resolution of the data from literature. We observe single fluorescently labeled cells over a complete cell cycle using confocal microscopy. Our goal is to acquire data of significantly higher quality than the existing data, which will allow for distinguishing between different models of cell growth.