Regensburg 2007 – wissenschaftliches Programm

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CPP: Fachverband Chemische Physik und Polymerphysik

CPP 19: POSTER: Micro and Nano Fluidics

CPP 19.6: Poster

Mittwoch, 28. März 2007, 16:00–18:30, Poster B

Discrete Microfluidics: Combinatorial Chemistry with Emulsions — •Venkatachalam Chokkalingam, Craig Priest, Stephan Herminghaus, and Ralf Seemann — Max Planck Institute for Dynamics and Self-Organization, D-37073 Göttingen, Germany

Microfluidics usually involves single phase liquids transported through microchannel networks. Instead of single phase flow we explore a droplet based discrete microfluidics for possible applications in combinatorial chemistry. The online generation of highly monodisperse emulsions in a single step is studied to compartment liquids within microchannels. Furthermore, we explore the manipulation of monodisperse emulsions using the distinct interaction of the internal length scale of the liquid (drop diameter) with the external provided geometry of the microchannels for positioning, sorting, dividing and exchanging droplets in 'lab-on-chip' style processing. Coalescence between adjacent compartments can be induced applying an electrical potential of a few volts across their lamella. As a first approach towards combinatorial chemistry we study all possible volumetric combinations of two chemicals. Adjusting the temporal concentration of the two chemicals accordingly to the channel geometry down stream when injecting them into the microfluidic channel leads to a 2D reaction library where the two concentration gradients vary along the x- and y-axis, respectively.