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DS: Fachverband Dünne Schichten
DS 23: Symposium: In situ Optics III
DS 23.3: Vortrag
Donnerstag, 29. März 2007, 10:30–10:45, H34
Vibrational sum frequency spectroscopy studies of poly(lactic acid) films — •magnus johnson1, albert sugiharto1, marc smits2, johannes nijsen3, and sylvie roke1 — 1Max-Planck Institute for Metals Research, Stuttgart, Germany — 2FOM-Institute AMOLF, Amsterdam, The Netherlands — 3Department of Nuclear Medicine, University Hospital, Utrecht, The Netherlands
In the search for biodegradable polymers with versatile applications, poly lactic acid (PLA) has proven to be a fruitful option. This polymer has successfully been used in the treatment of liver cancer [1] and in the repair of blood vessels, for example. [2]
In order to increase the knowledge of the complex bulk and surface structures of PLA, vibrational sum frequency spectroscopy (VSFS) has been employed on PLA films with varying crystallinity and stereo regularity. The structure of the films can be determined by mapping both the well understood stretching modes of the methyl groups as well as the skeletal modes that have vibrational energies far down into the fingerprint region. From these studies we are able to obtain a detailed image of the interface and the bulk, and experiments performed with different polarizations of the laser beams have enabled a deeper understanding of the orientation of various functional groups of the polymer. Additionally, we are able to track the changes in crystallinity in the films, initiated by annealing.
[1] Zielhuis, S.W. et. al. Biomaterials, 26, 925 (2005) [2] Postema, A.R.; Pennings, A.J. J. Appl. Polym. Sci., 37, 2351 (1989)