Regensburg 2007 – wissenschaftliches Programm
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DS: Fachverband Dünne Schichten
DS 27: Polymer and Composite Films
DS 27.3: Vortrag
Freitag, 30. März 2007, 10:00–10:15, H32
Antimicrobial properties of co-sputtered Ag,Au/PTFE nanocomposite films — •Vladimir Zaporojtchenko1, Rainer Podschun2, Amit Kulkarni1, Venkata Sai Kiran Chakravadhanula1, and Franz Faupel1 — 1Chair for Multicomponent Materials, Technical Faculty of CAU Kiel, Kaiserstrasse2, 24143 Kiel, Germany — 2Institute of Infection Medicine, CAU Kiel
In this work, we used co-sputtering of noble metals together with polytetraflourethylene(PTFE) as a method to produce antibacterial polymer/metal nanocomposite coatings, where the precious metals are only incorporated in a thin surface layer. Moreover, they are finely dispersed as nanoparticles, thus saving additional material and providing a very large effective surface for metal ion release. The nanocomposite films with the thickness between 100 and 300 nm were prepared in a large range of metal filling between 10 and 40 %. The antimicrobial effect of the nanocomposite coatings was evaluated by means of two different assays. Bactericidal activity due to silver release from the surface was determined by a modification of conventional disc diffusion methods. Inhibition of bacterial growth on the coated surface was investigated by a modified proliferation assay. Staphylococcus aureus was used mostly as test bacterium as this species commonly causes infections associated with medical polymer devices. The antibacterial efficiency of the coatings against different bacteria was demonstrated at extremely small noble metal consumption. The maximum ability of antibacterial effect was shown by the polymer/Ag-Au nanocomposite, followed by polymer/Ag nanocomposite.