Regensburg 2007 – wissenschaftliches Programm
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MM: Fachverband Metall- und Materialphysik
MM 35: SYBM Bioinspired Materials
MM 35.10: Vortrag
Donnerstag, 29. März 2007, 17:30–17:45, H16
Material and structural dynamics in trabecular bone — •R. Weinkamer1, D. Ruffoni1, J. Dunlop1, M. Hartmann2, Y. Brechet3, P. Roschger4, K. Klaushofer4, and P. Fratzl1 — 1Max Planck Institute of Colloids and Interfaces, Potsdam, Germany — 2C.E.A./Saclay, Gif-sur-Yvette, France — 3LTPCM, ENSEEG, Grenoble, France — 4Ludwig Boltzmann Institute of Osteology, Vienna, Austria
In trabecular bone different hierarchical levels contribute to its mechanical performance. In our simulation work we focus on the level of the foam-like architecture and on the inhomogeneity of the material bone itself. Two different processes are responsible for the ongoing changes on the structural and material level: the remodeling where small bone packets are continuously resorbed and deposited and the mineralization process where the mineral content increases in a newly deposited bone packet. The renewal of bone material is mechanically controlled, that is bone is deposited preferentially at mechanically highly loaded sites. Since the details of this control are unknown, a computer model with different realizations of the mechanical feedback loop has been employed, to study their influence on architecture and time evolution. With a separate model, the heterogeneous mineral content of bone at the material level was investigated. An increase in the mineral content results in a stiffer, but also more brittle material. Predictions are presented of the evolution of the frequency distribution of mineral content in situations of increased remodeling like in osteoporosis or in therapies which aim at reducing the remodeling.