Regensburg 2007 – scientific programme
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ST: Fachverband Strahlen- und Medizinphysik
ST 11: Strahlenrisiko
ST 11.2: Talk
Thursday, March 29, 2007, 14:00–14:15, Ch 12.0.16
Cancer risks of protracted exposure in the Techa River Cohort — •Markus Eidemüller1, Evgenia Ostroumova2, Ludmila Krestinina2, Alexander Akleyev2, and Peter Jacob1 — 1GSF - Forschungszentrum für Umwelt und Gesundheit, Institut für Strahlenschutz, 85764 Neuherberg — 2Urals Research Center for Radiation Medicine, Vorovsky St. 68-a, Chelyabinsk, 454076, Russia
We analyze solid cancer mortality in the Techa River Cohort who received protracted exposure in the 1950s from the release of radioactive material from the Mayak plutonium complex in the Southern Urals. The Extended Techa River Cohort includes 29849 people living along the Techa River between 1950 and 1960 with a total of 1854 solid cancer deaths until December 1999. The analysis is done in the framework of the biologically based two-step clonal expansion (TSCE) model. It is found that about 2.6% of all solid cancer deaths are caused by radiation exposure which corresponds to a significant radiation risk. The cohort shows an unusual pattern of radiation risk with age. Furthermore an analysis of the data with respect to genomic instability is presented.