Berlin 2008 – wissenschaftliches Programm

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BP: Fachverband Biologische Physik

BP 26: Posters II

BP 26.44: Poster

Donnerstag, 28. Februar 2008, 17:00–19:30, Poster A

Metabolic Synchronization of Yeast Cells — •Christian Warnke, Marcus J. B. Hauser, and Thomas Mair — Otto-von-Guericke-Universität Magdeburg, Institut für Experimentelle Physik, Abteilung Biophysik, Magdeburg, Germany

Yeast cells exhibit synchronization of their glycolytic activity when exposed to sugar. This behaviour is manifested as the appearance of oscillations in all intermediates of the glycolytiy pathway. The synchronization process is mediated via the extracellular exchange of the signalling molecule acetaldehyde, an intermediate of the glycolytic pathway. We have investigated the synchronization of yeast cells at varying extracellular acetaldehyde concentrations and at different metabolic states of the cells. We found a pronounced difference in the synchronization behaviour in response to acetaldehyde for the yeast strains Saccharomyces cerevisiae and Saccharomyces carlsbergensis. Our data indicate that these different behaviours can be explained by the different fermentative capacity of the two strains.