Dresden 2009 – scientific programme

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BP: Fachverband Biologische Physik

BP 25: Membranes

BP 25.6: Talk

Friday, March 27, 2009, 12:00–12:15, HÜL 186

Pattern formation in membranes by a translocation-diffusion mechanism — Sergio Alonso, •Sebastian Curth, and Markus Baer — Physikalisch-Technische Bundesanstalt, Berlin, Germany

We study the formation of protein patterns in the membranes of living cells by mathematical modelling. The formation of protein domains by electrostatic lipid-protein interactions and the nonequilibrium biochemical reaction cycle of proteins near the membrane give rise to complex dynamics. Here we consider an initially homogeneous membranes where the proteins self-organize into domains due to the competition between their attraction to the membrane and the interaction with different types of enzymes, which translocate the proteins from the membrane to the bulk. We incorporate also the regulation by calcium of the enzymes in the model.