Regensburg 2010 – scientific programme
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BP: Fachverband Biologische Physik
BP 21: Neurobiophysics and Sensory Transduction
BP 21.3: Talk
Wednesday, March 24, 2010, 14:45–15:00, H43
Independent components of neural activity in the auditory midbrain — •Dominika Lyzwa1, Dmitri Bibitchkov2, Hubert H. Lim3, and J. Michael Herrmann1,4 — 1Dept. Nonlinear Dynamics, MPI for Dynamics and Self-Organization, 37073 Göttingen, Germany — 2Dept. Membrane Biophysics, MPI for Biophysical Chemistry, 37077 Göttingen — 3Dept. Otolaryngology, Medical University, 30625 Hannover, Germany — 4IPAB, School of Informatics, University of Edinburgh, Edinburgh EH8 9AB, U. K.
We study mechanisms of sound encoding in the inferior colliculus (IC) which recently has become a new target for auditory implants. The analysis is based on neural recordings where double-tetrodes were used in the IC in cats for acoustic stimulation at various frequencies and volumes. The multi-dimensional data is projected to independent components that are obtained by Independent Component Analysis (ICA) using the Molgedey-Schuster algorithm (MS), FastICA and JADE. The single-trial components are then classified with respect to the stimulus properties. The classification proves best for low frequencies and volumes (1-2 kHz, 10-20 dB) and depends on the localisation in the inferior colliculus, where the stimulus is applied. The results of the data analysis are used to justify a numerical model of the encoding mechanism.