Regensburg 2010 – wissenschaftliches Programm
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BP: Fachverband Biologische Physik
BP 31: Posters: Membranes and Vesicles
BP 31.11: Poster
Donnerstag, 25. März 2010, 17:15–20:00, Poster B1
Lipid bilayers interacting with polymer chains: A Monte Carlo study — •Marco Werner1,2 and Jens-Uwe Sommer1,2 — 1Leibniz-Institut für Polymerforschung Dresden, Germany — 2Technische Universität Dresden - Institute for Theoretical Physics
We consider the interaction of amphiphile bilayers and polymer chains by a lattice based Monte Carlo method using the Bond Fluctuation Model [I. Carmesin and K. Kremer, 1988, Macromol. 21:2819]. To take advantage of the efficiency of this coarse graining method, we introduce explicit solvent to mediate the amphiphilic interactions. Therewith we observe stable bilayers spanned over the perdiodic boundary, which are formed spontaneously from a random initial state. We also obtain self-organized vesicles appearing in non-periodic boxes. By variation of bending stiffness for the hydrophobic tails we test the model to reproduce the crystalline phase as observed experimentally. We investigate the interactions between lipid bilayers and polymer chains for various chain lengths, chain densities and chain-solvent interactions. Our simulations show that hydrophobic chains are trapped within the hydrophobic layer of the membrane by changing conformations from dense globules into quasi 2D swollen coils. Manipulations of lipid bilayers using polymer chains can have interesting applications for drug delivery systems.