Regensburg 2010 – scientific programme
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BP: Fachverband Biologische Physik
BP 31: Posters: Membranes and Vesicles
BP 31.13: Poster
Thursday, March 25, 2010, 17:15–20:00, Poster B1
formation of planar lipid bilayer in a microfluidic chip — •jean-baptiste fleury1 and ralf seemann1,2 — 1Experimental Physics, Saarland University, D-66123 Saarbrücken, Germany — 2Max Planck Institute for Dynamics and Self-Organization, D-37073 Göttingen, Germany
We propose a new microfluidic approach to produce extremely stable planar lipid bilayer (until days), which can be directly observed with high optical quality. We demonstrate the formation of planar lipid bilayer by producing membrane domains as report in the literature [1]. This method furthermore provides a convenient tool for the analysis of self organization properties of proteins (or other active compounds) which are embedded into planar lipid bilayer, as we will demonstrate explicitly using gold nanoparticles.
[1] S. Mukherjee and all. Annu. Rev. Cell Dev. Biol. 20, 839 866 (2004).