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BP: Fachverband Biologische Physik

BP 33: Posters: Neurobiophysics

BP 33.4: Poster

Donnerstag, 25. März 2010, 17:15–20:00, Poster B1

Up- down state switching in a conductance- based cortical model — Hong-Viet Ngo, •Arne Weigenand, and Jens Christian Claussen — Institut für Neuro- und Bioinformatik, Universität zu Lübeck

In recent experiment [1] investigated the on- and off switching of bursting activity in ferret brain slices. This experiment is seen as a paradigmatic system towards the understanding of the emergence of cortical slow waves. The basic dynamics can be modeled by a simplified discretized integrate-and-fire model including inhibitory currents [2]. Here we use a conductance-based model to reproduce the spike-burst dynamics and the triggering of on-states as obeserved in [1].

[1] Y. Shu, A. Hasenstaub & D.A. McCormick. Nature 423, 288 (2003)

[2] Hong-Viet Ngo et al., submitted.