Regensburg 2010 – scientific programme

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DS: Fachverband Dünne Schichten

DS 35: Biomolecular and Functional Organic Layers I (Focused Session)

DS 35.3: Talk

Thursday, March 25, 2010, 18:00–18:15, H2

IR Spectroscopic Characterization of Carboxyl Acid-terminated Au Surfaces: Towards Biosensors — •Guoguang Sun¹, Marc Hovestädt², Xin Zhang³, Dana Maria Rosu¹, Bernhard Ay², Rudolf Volkmer², Jörg Rappich³, and Karsten Hinrichs¹ — ¹ISAS- Institute for Analytical Sciences, Department Berlin, Albert-Einstein-Str. 9, 12489 Berlin, Germany — ²Charité Universitätsmedizin Berlin, Institut für Medizinische Immunologie, Abteilung Molekulare Bibliotheken, Hessische Str. 3-4 , 10115 Berlin, Germany — ³Helmholtz-Zentrum Berlin für Materialien und Energie GmbH, Insitut für Silizium-Photovoltaik, Kekuléstr. 5, 12489 Berlin, Germany

Specific vibrational bands (C=O, amide I and amide II) were used for interpretation of IR spectra of the thin films (d<10 nm) achieved in every preparation step. The molecular interactions between the functional groups on the surface and the selected peptide as well as anti-glutathione S-transferase (GST) antibody were proved by IR ellipsometry spectra. The characteristic IR-spectra after antibody adsorption suggest that an IR-based biosensor could probably be built for an application.