Regensburg 2010 – wissenschaftliches Programm

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DY: Fachverband Dynamik und Statistische Physik

DY 6: Poster Session I

DY 6.22: Poster

Montag, 22. März 2010, 16:00–18:00, Poster B2

Application of the Maximum Entropie Method for Heterogeneous Diffusion Systems — •Mario Heidernätsch, Michael Bauer, and Günter Radons — Chemnitz University of Technology, D-09126 Chemnitz, Germany

Nowadays a range of experimental methods is used for the investigation of single molecule diffusion. Especially Single Molecule Tracking (SMT) and Fluorescence Correlation Spectroscopy (FCS) are suitable methods to probe small systems with high temporal or spatial resolution. However, as the examined systems became smaller, environmental inhomogeneities for instance on interfaces or of the surrounding liquid are causing observed heterogeneous diffusion processes. In FCS the Maximum Entropie Method (MEM) is a well tested technique to obtain a distribution of diffusivities from measured autocorrelation curves [1]. With the help of our distribution of scaled squared displacements [2] we are now able to apply the Maximum Entropie Method also in Single Molecule Tracking.

[1] P. Sengupta, K. Garai, J. Balaji, N. Periasamy, S. Maiti, Biophys. J. 84 (2003), pp 1977-1984

[2] M. Bauer, M. Heidernätsch, D. Täuber, C. von Borczyskowski, G. Radons, Diffusion Fundamentals III 11 (2009), pp. 70.1-70.2