Regensburg 2010 – scientific programme
Parts | Days | Selection | Search | Downloads | Help
O: Fachverband Oberflächenphysik
O 16: Organic, polymeric, biomolecular films - also with adsorbates
O 16.6: Talk
Monday, March 22, 2010, 16:15–16:30, H46
Protein resistant ethylene glycol terminated self-assembled monolayers by vapour deposition in vacuum — •Laxman Kankate1, Helge Großmann2, Udo Werner1, Robert Tampé2, Andrey Turchanin1, and Armin Gölzhäuser1 — 1Department of Physics, Physics of Supramolecular Systems, University of Bielefeld — 2Institute of Biochemistry, Johann Wolfgang Goethe-University, Frankfurt am Main
Vacuum vapour deposition (VD) is a method of choice for the preparation of organic interfaces for the in situ characterization and nanofabrication. However, it is usually difficult to prepare the self-assembled monolayers of thiols on gold by vacuum VD with the degree of quality sufficient for applications. Therefore, most of the SAM preparation is usually undertaken in solvents. In this contribution we report the first vacuum VD study of the protein resistant 11-(mercaptoundecyl)-triethylene glycol (C11EG3OH) SAM on gold surfaces. We present a comparison of C11EG3OH SAMs prepared by VD and by solution method using X-ray photoelectron spectroscopy and Fourier transform infrared reflection absorption spectroscopy. Using surface plasmon resonance spectroscopy we demonstrate that SAMs prepared by both methods have comparable protein resistivity to the adsorption of various proteins (bovine serum albumin, trypsin and myoglobin). These results show a new path to the in situ engineering of protein resistant surfaces and patterns by standard nanofabrication techniques.