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Dresden 2011 – scientific programme

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A: Fachverband Atomphysik

A 7: Poster I

A 7.5: Poster

Monday, March 14, 2011, 16:00–18:30, P1

Recent Improvements in Transport and Application of Hyperpolarized Xe-129 — •Maricel Repetto1, Mathis Düwel2, Werner Heil1, Hans W. Spiess2, Peter Blümler1, and Kerstin Münnemann21Johannes Gutenberg University, Institute of Physics, Mainz, Germany. — 2Max Planck Institute for Polymer Research, Mainz, Germany.

Hyperpolarized (HP) Xe-129 has numerous applications in medicine and fundamental physics. For separating HP Xe-129 from other gases used in the hyperpolarization process, it can be accumulated at 77K. The conditions of this process must be carefully evaluated in order to minimize polarization losses. Different devices and results for this separation process are presented. Additionally, HP Xe-129 must be transported to other sites (e.g. clinics). Therefore, the relaxation time, T1, must be kept as long as possible. Different strategies (e.g. admixing of gases and low-field storage) to achieve this goal are presented together with suitable home-build instrumentation to determine T1. Finally, the application to the patient must be realized in a rapid and biocompatible way. Here we found a very elegant solution by using oxygenation membranes, which dissolve Xe instantaneously and without foaming in any suitable carrier liquid or even blood.

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