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Dresden 2011 – scientific programme

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BP: Fachverband Biologische Physik

BP 16: Biological Membranes I

BP 16.9: Talk

Tuesday, March 15, 2011, 12:45–13:00, ZEU 260

The pico- to nanoscond dynamics in phospholipid bi- and monolayers — •Sebastian Busch1 and Tobias Unruh21Technische Universität München, Forschungs-Neutronenquelle Heinz Maier-Leibnitz (FRM II) and Physik Department E13, 85748 Garching bei München, Germany — 2Friedrich-Alexander-Universität Erlangen-Nürnberg, Lehrstuhl für Kristallographie und Strukturphysik, 91058 Erlangen, Germany

The dynamics of phospholipid molecules on the pico- to nanosecond time scale was studied with incoherent quasielastic neutron scattering.

Looking at stacks of bilayers [1], it was found that the observed motions of the molecules agree very nicely with preceding MD simulations [2]. The effect of several additives (except cholesterol) was negligible on this time scale [3].

In this contribution, we will concentrate on the evolution of the dynamics of the phospholipid molecules when going from stacks of bilayers to single bilayers (vesicles) and monolayers (as a stabilizing layer on oil-in-water dispersions).

[1] S. Busch et al., JACS 132(10):3232, 2010

[2] E. Falck et al., JACS 130(1):44, 2008

[3] S. Busch et al., BBA Biomembranes, in print,

doi:10.1016/j.bbamem.2010.10.012

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