Dresden 2011 – wissenschaftliches Programm
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BP: Fachverband Biologische Physik
BP 20: Neurobiophysics
BP 20.8: Vortrag
Mittwoch, 16. März 2011, 12:30–12:45, ZEU 250
Sensitive dependence on single spike perturbations in the dynamics of cortical circuits — Michael Monteforte1,2,3 and •Fred Wolf1,2,3 — 1Max Planck Institute for Dynamics and Self-Organization, Göttingen, Germany — 2Bernstein Center for Computational Neuroscience, Göttingen, Germany — 3Georg-August-University, Göttingen, Germany
London et al. [1] recently showed that triggering a single additional spike in a cerebral cortical neuron can cause an exponentially growing cascade of extra spikes in the network that largely decorrelate the network’s microstate. The network mechanism involved in this extreme sensitivity of cortical networks is currently not well understood. Here, we show in a minimal model of cortical circuit dynamics that exponential state separation after single spike and even single synapse perturbations can occur although the dynamics is stable to infinitesimal perturbations and rate responses are extremely weak. We present a conciliatory picture of exponentially separating flux-tubes around unique stable trajectories constituting the networks’ state spaces. [1] M. London, A. Roth, L. Beeren, M. Häusser and P. E. Latham, Nature 466, 123 (2010);