Dresden 2011 – wissenschaftliches Programm

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BP: Fachverband Biologische Physik

BP 30: Posters: Physics of Cells

BP 30.7: Poster

Donnerstag, 17. März 2011, 17:15–20:00, P3

Manipulation of magnetic particles in living cells — •Haleh Ebrahimian — Bielefeld University ,Thin Films and Physics of Nanostructures , Bielefeld,Germany

In recent years, the so called Lab-on-the-chip system was developed and miniaturized for hand held applications. This system can also be extended for the analysis of heat stress or signaling pathways by the manipulation of magnetic particles in living cells. For the manipulation of particles inside cells, three different steps are required:

1.Moving of particles by magnetic forces outside of cells. The manipulation had been done by magnetic forces which was generated by conducting lines applying 1.2 V.

2.Injection of particles into cells 1um diameter magnetic particles were injected into living cells of a fungus (Mucor mucedo),a protoplast of Cress (Arabidopsis thaliana), and a epidermis protoplast of barley (Hordeum vulgare)

3.Positioning of cells by special trapping design in a micro-fluidic channel.

The aim of this work is the penetration and movement of single magnetic particles into the cells on Lab-on-the-chip system.