Dresden 2011 – wissenschaftliches Programm
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BP: Fachverband Biologische Physik
BP 34: New Technologies
BP 34.5: Vortrag
Freitag, 18. März 2011, 11:45–12:00, ZEU 260
Dip-Pen Nanolithography and Polymer-Pen Lithography for Bio-Medical Applications — •Falko Brinkmann1,2,3,4, Sylwia Sekula1, Michael Hirtz1, and Harald Fuchs1,2,3 — 1Institut für Nanotechnologie, Karlsruher Institut für Technologie, 76128 Karlsruhe — 2Physikalisches Institut, Westfälische Wilhelms-Universität Münster, 48149 Münster — 3Center for Nanotechnology (CeNTech), 48149 Münster — 4Institut für Tumorbiologie, Universitätsklinikum Hamburg-Eppendorf, 20246 Hamburg
Dip-Pen Nanolithography (DPN) is a versatile tool for the fabrication of arbitrary patterns on a wide range of surfaces. It uses the tip of an atomic force microscope (AFM) as a miniature quell-pen which is dipped into inks like silanes or phospholipids. Its capability to pattern different functional materials on the same surface with 1D or 2D tip arrays simultaneously (multiplexing) leads to wide interest in biology and medicine. Feature sizes range from less than 100 nm to the several micrometers.
Polymer-Pen Lithography (PPL) is based on a polydimethysiloxane (PDMS) stamp with millions of tips. Compared to silicon tip arrays, polymer pens are inexpensive and are able to deposit inks with higher throughput. Multiplexed dot-arrays can be accomplished in nanometer resolution over many square centimeters within a few minutes.
Both DPN and PPL can be used to fabricate functional nano- and micropatterns for bio-medical studies like protein-binding, virus-detection and cell-adhesion with potential application in biosensors and medical lab-on-chip devices.