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CPP: Fachverband Chemische Physik und Polymerphysik

CPP 35: Poster: Micro- and Nanofluidics

CPP 35.15: Poster

Mittwoch, 16. März 2011, 17:00–19:00, P2

Microfluidic sorting of chiral particles — •Maria Zvyagolskaya and Clemens Bechinger — Universität Stuttgart, 2. Physikalisches Institut, Pfaffenwaldring 57, 70569 Stuttgart

Molecules of opposite chirality, so-called enantiomeres, show different binding affinity to other molecules which may lead to unwanted chemical reactions. Therefore , sorting of molecules with different chiralities is an important task in molecular biology or pharmaceutical industry. Here, we experimentally study a separation method based on hydrodynamic forces acting on chiral particles in microfluidic vortices [1]. Three-dimensional chiral particles on a length scale of micrometers are created by a photolithographic process and labelled with fluorescent dyes according to their chirality. We study the motion of such particles in microfluidic channels with different types of rotational flows and investigate how spatial distribution of particles in a vortex corresponds to its chirality.

[1] M. Kostur, M. Schindler, P. Talkner, and P. Hänggi, Phys. Rev. Lett. 96, 014502 (2006).