Dresden 2011 – wissenschaftliches Programm

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DY: Fachverband Dynamik und Statistische Physik

DY 10: Posters I

DY 10.38: Poster

Montag, 14. März 2011, 17:00–19:00, P4

State switching in a conductance-based cortical model: phase diagram and pulse stimulation — •Arne Weigenand, Thomas Martinetz, and Jens Christian Claussen — Neuro- and Bioinformatik, Universität zu Lübeck

A recent experiment [1] investigated the on- and off switching of bursting activity in ferret brain slices. This experiment is seen as a paradigmatic system towards the understanding of the emergence of cortical slow waves. The basic dynamics can be modeled by a simplified discretized integrate - and - fire model having intrinsic inhibitory currents but lacking inhibitory connections [2]. Here we use a conductance-based model to reproduce the spike-burst dynamics and the triggering of Up states as observed in [1]. Finally we investigate the phase diagram of the qualitatively different network states depending on the coupling strength and network noise intensity [3].

[1] Y. Shu, A. Hasenstaub, and D. A. McCormick, Nature 423, 288 (2003). [2] H. V. Ngo, J. Köhler, J. Mayer, J. C. Claussen, and H. G. Schuster, EPL 89, 68002 (2010) [3] A. Weigenand et al., in preparation