Dresden 2011 – scientific programme

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Q: Fachverband Quantenoptik und Photonik

Q 15: Poster 1: Quanteninformation, Quanteneffekte, Laserentwicklung, Laseranwendungen, Ultrakurze Pulse, Photonik

Q 15.58: Poster

Monday, March 14, 2011, 16:30–19:30, P1

Flow measurements by the phase-resolved Doppler OCT and the signal power decrease in Spectral Domain OCT — •Julia Walther and Edmund Koch — Clinical Sensoring and Monitoring, Faculty of Medicine Carl Gustav Carus, Dresden University of Technology, Fetscherstr. 74, 01307 Dresden, Germany

Optical Coherence Tomography (OCT) is a non-invasive, contactless imaging modality in medical diagnosis and biomedical research providing cross-sectional images of internal structures of highly scattering samples with micrometer resolution. Spectral Domain OCT (SD OCT), based on the spectrometer analysis of the interference signal, is gaining considerable interest due to its high sensitivity and high image acquisition speed. Nowadays, SD OCT structural imaging is extended with functional studies for the determination of physiology and functional impairment of diseases. The phase-resolved Doppler method is based on the linear relation of the phase difference of adjacent interference signals and the axial sample velocity and is often used to measure blood flow velocities in small vessels. Unfortunately, this technique can be inflamed due to high sample velocities during the integration time resulting in a signal power decrease of the backscattering signal. We propose to take advantage of the signal damping for the quantification of high flow velocities at which the standard Doppler OCT does not work any longer. Furthermore, a combination of the established Doppler OCT and the numerically simulated signal damping due to obliquely moved scatterers is presented for an in vitro 1% Intralipid flow phantom study.