Dresden 2011 – scientific programme
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ST: Fachverband Strahlen- und Medizinphysik
ST 2: Radiation and Medical Physics Posters
ST 2.7: Poster
Monday, March 14, 2011, 17:00–18:00, P2
Development of a mobile dynamic nuclear polarizer for continuous flow applications — •Sandro Ebert1, Björn Dollmann1, Christian Bauer1, Michael Kölzer1, Peter Blümler2, Hans W. Spiess1, Dariush Hinderberger1, and Kerstin Münnemann1 — 1Max Planck Institute for Polymer Research, Mainz, Germany — 2Johannes Gutenberg University, Institute of Physics, Mainz, Germany
Despite its wide applicability in natural science, NMR still suffers from its inherently low sensitivity. This could be overcome by hyperpolarization of molecules via dynamic nuclear polarization (DNP). Here, we introduce a mobile DNP polarizer, based on an inexpensive Halbach magnet operating at 0.35 T. It shows an almost vanishing magnetic flux at its outer side and is not disturbing other instruments. It can be placed directly next to a superconducting magnet, thus limiting the transport time of the hyperpolarized sample. It will be shown, that the Halbach magnet has the same DNP performance like an electromagnet. Although DNP methods have found important applications in science, two problems remain: Firstly radicals are needed, which are mostly toxic. This problem becomes crucial with regard to medical applications. Secondly, the sample must be transported from the polarization magnet to the place of detection and polarization losses due to T1 occur. We are currently implementing a flow system to the mobile DNP polarizer, which should overcome both obstacles. The radicals will be immobilized in a gel matrix and the hyperpolarized radical free fluid is pumped subsequently directly in the MRI scanner.