Dresden 2011 – scientific programme

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ST: Fachverband Strahlen- und Medizinphysik

ST 5: Imaging with Ionizing Radiation I

ST 5.6: Talk

Thursday, March 17, 2011, 11:15–11:30, POT 112

Tumour visualisation in human soft tissue using grating-based X-ray phase contrast imaging — •Julia Herzen, Marian Willner, Simone Schleede, Martin Bech, Arne Tapfer, Marco Stockmar, Klaus Achterhold, and Franz Pfeiffer — Department of Physics (E17) and Institute of Medical Engineering (IMETUM), Technische Universität München, Germany

The grating-based phase-contrast imaging provides enhanced image structure details, which are partly complementary or even not attainable with standard x-ray absorption imaging. Especially in the case of biological soft tissue when standard x-ray radiography is often limited due to the weak absorption contrast, this method represents a real alternative. Based on x-ray optical transmission gratings this modality has transferred the phase-contrast imaging from the highly brilliant synchrotron radiation sources to conventional laboratory-based broadband x-ray tubes. Here, we present a study on human soft tissue specimens containing tumours using the grating-based phase contrast imaging at both highly brilliant synchrotron (ESRF, Grenoble), and at conventional X-ray laboratory radiation sources. Our results demonstrate a superior contrast for different kinds of soft tissue in the phase contrast and verify this imaging modality to be a promising candidate to establish phase-contrast imaging in clinical radiology.