Berlin 2012 – scientific programme

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BP: Fachverband Biologische Physik

BP 18: Posters: Statistical Physics in Biological Systems

BP 18.15: Poster

Wednesday, March 28, 2012, 17:30–19:30, Poster A

Understanding electrical currents in DNA translocation experiments — •Stefan Kesselheim and Christian Holm — Institut für Computerphysik, Universtät Stuttgart

DNA translocation through synthetic nanopores is considered a technologically promising candidate for rapid DNA sequencing and is physically interesting because the experiments allow to probe single DNA molecules. The most important observable, the electrolyte-based conduction is only partly understood. We analyze this situation from different perspectives and show many different effects are important: We discuss an complex interplay of attraction of counterions, steric exclusion of ions, hydrodynamic interactions, ion correlations and electrofriction. Our analysis tool is molecular dynamics simulation including hydrodynamic interaction by means of the Lattice-Boltzmann method.