Berlin 2012 – scientific programme

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BP: Fachverband Biologische Physik

BP 24: Posters: DNA/RNA and Related Enzymes

BP 24.3: Poster

Thursday, March 29, 2012, 17:30–19:30, Poster A

Models of Base Excision Repair — •Laurin Lengert — TU Darmstadt, Hessen

Our goal is to study simple models of DNA repair networks. One such network is the base excision repair network which is involved in the repair of single strand breaks. We will discuss the minimal set of repair proteins needed for a model that is able to reproduce the time course of protein recruitment data revealed by experiments. Furthermore, we will analyze how the properties of these simple models affect the data produced in computer simulations. This in turn enables us to interpret various features of the experimental curves in terms of the underlying processes.