Berlin 2012 – wissenschaftliches Programm
Bereiche | Tage | Auswahl | Suche | Aktualisierungen | Downloads | Hilfe
BP: Fachverband Biologische Physik
BP 24: Posters: DNA/RNA and Related Enzymes
BP 24.5: Poster
Donnerstag, 29. März 2012, 17:30–19:30, Poster A
mechanical properties of DNA through numerical method and monte carlo simulation — •hassan chatrsahar1 and mohammad hossein yamani2 — 1Islamic Azad University of Takestan, Takestan, Iran — 2Johannes Gutenberg University, Mainz, Germany
DNA as an anisotropic flexible polymer contains bioinformation of all living cells. Interactions between DNA and proteins that cause deformations in the structure of DNA are essentially ubiquitous during many life processes inside cells. We study the persistence length of DNA in two and three dimensions, considering the elastic bending anisotropy and twist-bend coupling through Worm-Like Chain model (WLC) and Metropolis Monte Carlo simulation. We compare the persistence length of DNA in two and three dimensions. We show although twist-bend coupling does not affect the persistence length in three dimensions, it increases the persistence length in two dimensions by a few percents. Also, through Elastic Rod model we derive the energy equation of a deformed DNA and by minimizing the conformation energy and solving the equations through numerical method, the spatial conformation of a DNA under various boundary conditions and integral constrains is studied. After that, effects of the twist-bend coupling and anisotropy in DNA conformation and its energy are probed.