Berlin 2012 – scientific programme

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BP: Fachverband Biologische Physik

BP 3: Statistical Physics of Biological Systems I (with DY)

BP 3.8: Talk

Monday, March 26, 2012, 11:30–11:45, MA 001

Generalized Entropies for Clustering, e.g., in Molecular Evolution — •Kay Hamacher — TU Darmstadt, 64287 Darmstadt, Germany

Entropy is a key concept in information theory. Analysis of empirical data is often improved by relying on (relative) entropies. In this talk I want to describe current progress in clustering approaches by optimization techniques [1-2] applied to entropy distances via generalized entropy concepts [3], in phylogenies [4,5], finite-size effects in empirical data [6], and in molecular design [7].

[1] K. Hamacher. J.Comp.Phys., 227(2):1500-1509, 2007

[2] K. Hamacher. Europhys.Lett. 74(6):944, 2006

[3] R. Bose, G. Thiel, K. Hamacher. Variation in Local Entropy to Cluster Genomic Sequences, submitted, 2011.

[4] K. Hamacher. Proc. of BIOINFORMATICS 2010, p. 114-122, A. Fred, J. Filipe, H. Gamboa (eds.), ISBN 978-989-674-019-1

[5] K. Hamacher, Information Theoretical Dissection of the Holobiont - Host-Virus Interaction as an Example, Nova Acta Leopoldina, accepted, 2011

[6] P. Weil, F. Hoffgaard, K. Hamacher. Comp. Biol. Chem. 33:440-444, 2009

[7] K. Hamacher. J.Comp.Chem., 28(16):2576-2580, 2007