Berlin 2012 – wissenschaftliches Programm
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BP: Fachverband Biologische Physik
BP 32: Physics of Cells III
BP 32.11: Vortrag
Freitag, 30. März 2012, 12:15–12:30, H 1028
Measurement of adhesion forces of bacteria on controlled hydroxyapatite surfaces — •Christian Zeitz1, Peter Loskill1, Markus Bischoff2, Mathias Herrmann2, and Karin Jacobs1 — 1Saarland University, Experimental Physics, D-66041 Saarbrücken, Germany — 2Saarland University Hospital, Microbiology and Hygiene, D-66421 Homburg/Saar, Germany
The aim of the study presented here is to probe the adhesive properties of bacteria on hydroxyapatite (HAP) surfaces. However, "real" surfaces like teeth are very complex due to their natural variation in structure, roughness and chemical composition. Therefore, artificial HAP samples have been prepared, a characterization of which is presented in this work. The sample surface is very smooth (local RMS roughness below 1 nm) and, thus, allows controlled AFM adhesion measurements with bacterial probes. The HAP samples can be fluoridated [1] and the adhesion strength of Staphylococcus epidermidis, Streptococcus oralis and Streptococcus mutans can be probed on both types of surfaces. The results suggest an alternative explanation for the efficiency of fluoridation of teeth for the prevention of cavities.
[1] F.Müller et al., Langmuir, 2010, 26 (24), p 18750