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BP: Fachverband Biologische Physik

BP 8: Posters: Biopolymers and Biomaterials (with CPP)

BP 8.6: Poster

Monday, March 26, 2012, 17:30–19:30, Poster A

Tissue growth as mass generation in a linear elastic medium — •Niko Komin, Lars Ole Schwen, and Tobias Preusser — Fraunhofer MEVIS, Bremen, Germany

The liver as a major metabolic organ fulfils a huge variety of vital metabolic tasks in a mammalian organism. Its great ability to regenerate after injury allows for the transplantation of a large part of the organ from a living donor to a recipient in need. Liver mass and function is restored within a matter of months after operation.

In the talk we will present the regeneration process as the generation of mass (tissue) within a linear elastic medium. Cell proliferation depends on nutrition via the regrowing vascular structure and the topology of the vascular structure is governed by optimization criteria. We will present modelling techniques and results.