Berlin 2012 – wissenschaftliches Programm
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MM: Fachverband Metall- und Materialphysik
MM 56: Biomaterials
MM 56.2: Vortrag
Donnerstag, 29. März 2012, 16:00–16:15, H 0106
Influence of the synthetic polypeptide c25-mms6 on Nanoparticle growth — •Annalena Wolff1, Katrin Wollschläger2, Katrin Eckstädt1, Inga Ennen3, Patrick Thomas1, Walid Hetaba3, Stefan Löffler3, Marco Wissbrock2, Nadine Mill1, Thomas Weiß1, Peter Schattschneider3, Norbert Sewald2, and Andreas Hütten1 — 1Universität Bielefeld, Fakultät für Physik, Deutschland — 2Universität Bielefeld, Fakultät für Chemie, Deutschland — 3Technische Universität Wien, Institut für Festkörperphysik,Österreich
Bioinspired Nanoparticle syntheses have advanced in recent years. Polypeptides play a key role in the controlled biomineralization process. Their influence on inorganic crystal growth has not yet been understood. A bioinspired synthesis of Cobalt Ferrite nanoparticles was carried out in vitro at room temperature. Here a short synthetic version of the protein MMS6, found to be involved in the biomineralization process within Magnetotactic Bacteria was used to synthesize the magnetic nanoparticles. The influence of this synthetic polypeptide was studied by comparing the obtained Cobalt Ferrite Nanoparticles to those synthesized without polypeptide. Stoichiometric Cobalt Ferrite Nanoparticles were obtained in the polypeptide enhanced synthesis while non-stoichiometric Cobalt Ferrite nanoparticles were found in the control experiment. Our results indicate that the polypeptide influences the microstructure but is not required to obtain particles. On the basis of our results we propose a multistep biomineralization process in which the polypeptide acts as a catalyst.