Berlin 2012 – scientific programme
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ST: Fachverband Strahlen- und Medizinphysik
ST 2: Advanced Diagnostic Imaging II
ST 2.4: Talk
Monday, March 26, 2012, 16:20–16:40, HFT-FT 101
Improved Diagnostic Differentiation of Renal Cystic Lesions with X-ray Phase-Contrast Computed Tomography — •Julia Herzen1, Marian Willner1, Peter Noel2, Alexander Fingerle2, Daniela Münzel2, Dieter Hahn1, Ernst J. Rummeny2, and Franz Pfeiffer1 — 1Department of Physics & Institute for Medical Engineering, Technische Universität München, Garching, Germany — 2Department of Radiology, Technische Universität München, Munich, Germany
The diagnostic value of X-ray phase-contrast computed tomography (PCCT) is one of the unexplored areas in medical imaging; at the same time, it seems to offer the opportunity as a highly sensitive diagnostic tool. Conventional computed tomography (CT) has had an enormous impact on medicine, but it is limited in soft-tissue contrast. One example that portrays this challenge is the differentiation between benign and malignant renal cysts. In this work we report on a study of characterizing renal cysts using PCCT. We imaged a renal phantom with grating-based PCCT system using a rotating anode X-ray tube and a photon-counting detector. The phantom consisted of a renal equivalent soft-tissue and cystic lesions grouped in non-enhancing cyst and hemorrhage series and an iodine enhancing series. We found that with PCCT an improved differentiation between hemorrhage renal cysts from contrast enhancing malignant cysts is possible without using any contrast agents.