Berlin 2012 – scientific programme
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ST: Fachverband Strahlen- und Medizinphysik
ST 4: Poster
ST 4.12: Poster
Tuesday, March 27, 2012, 10:10–11:30, Poster F
Imaging analysis of heart movement for improving the respiration-gated radiotherapy in patients with left sided breast cancer — Rania Abdelhamid1, A. Farrag1, A. Khalifa1, and •Andreas Block2 — 1Clinical Oncology Department, Assuit University — 2Institute for Medical Radiation Physics
Respiration induced heart movement during radiotherapy exposes the heart to the inevitable risks of radio-exposure, and hence radiation injury, in cases of Lt. sided breast cancer. The impact of such a risk is additionally aggravated by the use of radiotherapy in combination with cardiotoxic chemotherapeutic agents. Radio-oncologists pay special attention to the coronary arteries that might be included in this small part of the heart exposed to radiation. The aim of this study was to include the internal heart movement for improving respiration-gated radiotherapy of left sided breast cancer. For 70 patients, all females left sided breast cancer, two planning CT's in inspiration and expiration, and one free breathing scan are performed. The heart motion was analyzed with the clinic-developed software ORAT in the simulator sequence for acquiring information of the cranio-caudal amplitude of heart movements in free breathing (respiration-induced amplitude) and a 15 seconds breath-hold phase (inherent amplitude). The role of inherent heart movement varies from one patient to another which should be taken in consideration during defining the parameters of respiration-gated radiotherapy. The inherent amplitude of the heart motion is the physiological lower limit of the respiration-gating window.