Stuttgart 2012 – wissenschaftliches Programm
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Q: Fachverband Quantenoptik und Photonik
Q 54: Poster 3
Q 54.58: Poster
Donnerstag, 15. März 2012, 16:30–19:00, Poster.I+II
Nanodiamonds for biological application — •Anna Ermakova1, Boris Naydenov1, Fedor Jelezko1, Rolf Reuter2, Jörg Wrachtrup2, Goutam Pramanik3, and Tanja Weil3 — 1Institute for Quantum Optics, University Ulm, Germany — 23. Physical Institute, University Stuttgart, Germany — 3Institute of Organic Chemistry III, University Ulm, Germany
Diamond is good material for biological and medical application, since it is highly biocompatible diamond and its surface can be functionalized and covered with active molecules. This very interesting for nanodiamonds which have large specific surface area the are small enough in order to move inside the cell. At the same time small diamond nanoparticles (2-10 nm) have been shown to be non-toxic for a variety of cells, compared to different dyes. Moreover, diamond contains a variety of photostable defects. Where the nitrogen-vacancy center [NV] is the most promising one. Nanodiamonds containg NV allow the detection of small magnetic field with high spatial resolution and sensitivity.
In this work we present motional dynamics of nanodiamonds coated with a novel peptide-polymer hybrid poly(ethylene oxide) (cBSA-PEO) marked with Rhodamine in the solution. The successful coating of nanodiamond with cBSA-PEO has been confirmed by emission from NV centers. The higher colloidal stability of this nanodiamonds in the solution with high ionic strength was determined by fluorescence correlation spectroscopy.